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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRRT All Species: 39.09
Human Site: Y175 Identified Species: 86
UniProt: Q9BXP5 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXP5 NP_001122324.1 876 100666 Y175 A V K R Y N D Y K L D F R R Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001106640 860 98726 Y175 A V K R Y N D Y K L D F R R Q
Dog Lupus familis XP_536858 879 101306 Y190 A V K R Y N D Y K L D F R R Q
Cat Felis silvestris
Mouse Mus musculus Q99MR6 875 100434 Y175 A V K R Y N D Y K L D F R R Q
Rat Rattus norvegicus XP_001076594 762 87510 Y175 A V K R Y N D Y K L D F R R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis B1H1X4 849 98562 Y175 A V K R Y N D Y K I D F R R Q
Zebra Danio Brachydanio rerio Q66I22 896 103255 Y179 S V K R Y N E Y K I D F R R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9K7 943 107203 Y181 V M R K Y T E Y K T D F K R Q
Honey Bee Apis mellifera XP_396542 894 101991 Y174 A I K R Y N E Y K L E F R R Q
Nematode Worm Caenorhab. elegans Q966L5 712 80776 K154 A H L E N V Q K R L Q V F N E
Sea Urchin Strong. purpuratus XP_787830 934 107085 Y172 A V K K Y N A Y K L E F H K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.8 96.8 N.A. 97.7 84.9 N.A. N.A. N.A. 69.8 70.4 N.A. 42.2 48.4 37.5 46.4
Protein Similarity: 100 N.A. 97 97.6 N.A. 98.7 85.8 N.A. N.A. N.A. 81.3 80.4 N.A. 57.6 65.5 52 60.9
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 93.3 80 N.A. 46.6 80 13.3 60
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 100 100 N.A. 80 100 26.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 82 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 55 0 0 0 73 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 28 0 0 0 19 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 91 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 19 0 0 0 0 0 % I
% Lys: 0 0 82 19 0 0 0 10 91 0 0 0 10 10 0 % K
% Leu: 0 0 10 0 0 0 0 0 0 73 0 0 0 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 82 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 82 % Q
% Arg: 0 0 10 73 0 0 0 0 10 0 0 0 73 82 0 % R
% Ser: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % T
% Val: 10 73 0 0 0 10 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 91 0 0 91 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _